Pathological Analysis of Lipoprotein(a) Risk Variants and Culprit Coronary Thrombotic Lesions
May 14th, 2026CVPath’s research letter, led by Dr. Tatsuya Shiraki, was recently published in JAMA Cardiology. This paper examines the association between…
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The Silent Culprit: Why ‘Hidden’ Plaque Ruptures Matter
March 18th, 2026CVPath’s editorial on the work of R. Kakizaki et al. has been published in the European Heart Journal. It focuses…
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Pathophysiology of Coronary Restenosis
February 9th, 2026Representative histologic images of bare metal and drug-eluting stents after implantation. In-stent restenosis (ISR) refers to the narrowing of the…
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Architects of Decay: How Fibroblast-like Mesenchymal Cells Shape the Necrotic Core
January 29th, 2026CVPath’s editorial commentary on the work of Morales‑Cano et al. has been published in the journal Cardiovascular Research. The authors…
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Lipid-Related Polygenic Risk Score and Its Association with Plaque Rupture Versus Erosion
December 23rd, 2025CVPath recently had a research paper published in Arteriosclerosis, Thrombosis, and Vascular Biology, led by Dr. Tomoyo Hamana, focusing on…
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Recent Advances in Single-Cell Analysis of Atherosclerotic Plaque Biology
December 16th, 2025Classical model of atherosclerotic plaque development based on the response-to-injury hypothesis. (LDL = low-density lipoprotein; SMC = smooth muscle cell.)…
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Do Biodegradable Polymer Stents Have a Large Impact in Small Vessels?
November 13th, 2025Comparative histopathology of durable polymer-drug eluting stent (DP-DES) and biodegradable polymer-drug eluting stent (BP-DES) in small vessel coronary artery disease.…
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Coronary Artery Calcification Scoring and Plaque Types in Sudden Deaths
September 26th, 2025A distinct feature of atherosclerosis is coronary artery calcification (CAC), which is often measured by computed tomography (CT) and CAC…
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A Pharmacokinetic Comparison Between Three Drug Delivery Devices in Porcine Coronary Arteries
September 25th, 2025Catheter-based drug-delivery systems such as drug-coated balloons are widely used in percutaneous coronary intervention (PCI). However, they each have different…
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Comparison of Vascular Injury from Intravascular Lithotripsy, Cutting, or Ultra-High-Pressure Balloons During Coronary Calcium Modification
September 24th, 2025Successful percutaneous coronary intervention (PCI) involves the effective modification of heavily calcified coronary lesions. Commonly used methods include intravascular lithotripsy…
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