CVPath Yearly Summary 2019-2020 – Dr. Aloke Finn, Medical Director
Dear CVPath Friends and Colleagues,
On behalf of everyone here at CVPath, it is my pleasure to wish you, your families and your teams a happy, safe, and productive New Year.
We would also like to thank you for your friendship and continued support of CVPath. It has been a productive year for the Institute, including notable achievements and developments.
- Our core pathology team welcomed the addition of Dr. Dipti Surve as Head of Molecular Pathology. Surve did her residency in anatomic and clinical pathology at Georgetown Medstar Hospital. She’s board-certified in Anatomic Pathology, Clinical Pathology, Hematopathology, and Molecular Genetic Pathology. Her presence at CVPath strengthens our expertise in cardiac pathology as well as device analysis.
- In December, we launched our new website (cvpath.org) and logo which reflects our commitment to providing our sponsors and research partners with cutting edge technologies and biobanks, important resources used for advancing vital new discoveries in cardiovascular medicine and its treatment.
- On the publications front, CVPath had a banner year.
- In March, we wrote an editorial on the role of Hepcidin in Atherosclerosis in Arteriosclerosis, Thrombosis, and Vascular Biology (PMID 30811251), followed by a review article in September in EbioMedicine (PMID 31416722) on the role of iron in atherosclerosis and inflammation.
- In May, we published a review in Nature Reviews Cardiology on “Fully Bioabsorbable Vascular Scaffolds” (PMID 30546115). It highlighted both the promises and pitfalls of this technology, as well as, future directions for the field.
- July brought a review of the preclinical data supporting the use of drug-eluting coronary stents, again in Nature Reviews Cardiology (PMID 31346257).
- In August, we published an original research article in JACC: Cardiovascular Imaging on “Histologic Characterization of Peripheral Arteries in Subjects with Abundant Risk Factors” (PMID 30553660), describing the pathology findings of peripheral arterial disease of the lower extremities and making important correlations with imaging modalities.
- In December, we wrote an original research article on the role of coronary calcification and its impact on stent healing which was published in the European Heart Journal (PMID 31803916).
- We also edited a textbook on coronary calcification (and wrote two chapters in it), describing the current understanding of the biology of vascular calcification, its use in screening and its interventional management (https://www.sciencedirect.com/book/9780128163894/coronary-calcium).
Additionally, we completed our first year of the prestigious Leducq Transatlantic Research Networks of Excellence grant, which CVPath was awarded in 2018 together with several other U.S. and European partners. The project is “Defining the Roles of Smooth Muscle Cells and Other Extracellular Matrix Producing Cells in Late-Stage Atherosclerotic Plaque Pathogenesis.” This award facilitates our work with several leading research centers, including the University of Virginia and the University Medical Center in Utrecht, Netherlands.
In the coming year, watch for new research findings from CVPath in the fields of structural heart repair, drug-coated balloons, drug-eluting stents, as well as, many other vascular devices.
Thank you again for your continued support of the CVPath Institute. Dr. Virmani, and our colleagues, join me in looking forward to working with you in the New Year. Please don’t hesitate to contact me with any questions you might have.
Aloke Finn MD