Publications

Atherosclerosis

  1. Yahagi K, Davis HR, Arbustini E, Virmani R. Sex differences in coronary artery disease: Pathological observations. Atherosclerosis. 2015 Mar;239(1):260-267. doi: 10.1016/j.atherosclerosis.2015.01.017. Epub 2015 Jan 20. Review. PMID: 25634157
  2. Kwak BR, Bäck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJ, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ, Evans PC. Biomechanical factors in atherosclerosis: mechanisms and clinical implications. Eur Heart J. 2014 Nov 14;35(43):3013-20, 3020a-3020d. doi: 10.1093/eurheartj/ehu353. Epub 2014 Sep 17. PMID: 25230814
  3. Thiele JR, Habersberger J, Braig D, Schmidt Y, Goerendt K, Maurer V, Bannasch H, Scheichl A, Woollard KJ, von Dobschütz E, Kolodgie F, Virmani R, Stark GB, Peter K, Eisenhardt SU. Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy. Circulation. 2014 Jul 1;130(1):35-50. doi: 10.1161/CIRCULATIONAHA.113.007124. Epub 2014 Apr 28. PMID: 24982116
  4. Sen SK, Boelte KC, Barb JJ, Joehanes R, Zhao X, Cheng Q, Adams L, Teer JK, Accame DS, Chowdhury S, Singh LN; NISC Comparative Sequencing Program; CHARGE Consortium, Kavousi M, Peyser PA, Quigley L, Priel DL, Lau K, Kuhns DB, Yoshimura T, Johnson AD, Hwang SJ, Chen MY, Arai AE, Green ED, Mullikin JC, Kolodgie FD, O’Donnell CJ, Virmani R, Munson PJ, McVicar DW, Biesecker LG.  Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification. Am J Hum Genet. 2014 Jul 3;95(1):66-76. doi: 10.1016/j.ajhg.2014.06.003. Epub 2014 Jun 26.  PMID: 24975946
  5. Yahagi K, Otsuka F, Sakakura K, Sanchez OD, Kutys R, Ladich E, Kolodgie FD, Virmani R, Joner M. Pathophysiology of superficial femoral artery in-stent restenosis.
    J Cardiovasc Surg (Torino). 2014 Jun;55(3):307-23. Review.  PMID: 24755699
  6. Hsu S, Koren E, Chan Y, Koscec M, Sheehy A, Kolodgie F, Virmani R, Feder D. Effects of everolimus on macrophage-derived foam cell behavior.  Cardiovasc Revasc Med. 2014 Jul-Aug;15(5):269-77. doi: 10.1016/j.carrev.2014.05.007. Epub 2014 May 22. PMID: 24972512
  7. Pu J, Mintz GS, Biro S, Lee JB, Sum ST, Madden SP, Burke AP, Zhang P, He B, Goldstein JA, Stone GW, Muller JE, Virmani R, Maehara A.  Insights into echo-attenuated plaques, echolucent plaques, and plaques with spotty calcification: novel findings from comparisons among intravascular ultrasound, near-infrared spectroscopy, and pathological histology in 2,294 human coronary artery segments.  J Am Coll Cardiol. 2014 Jun 3;63(21):2220-33. doi: 10.1016/j.jacc.2014.02.576. Epub 2014 Mar 26.  PMID: 24681142
  8. Tahara N, Mukherjee J, de Haas HJ, Petrov AD, Tawakol A, Haider N, Tahara A, Constantinescu CC, Zhou J, Boersma HH, Imaizumi T, Nakano M, Finn A, Fayad Z, Virmani R, Fuster V, Bosca L, Narula J. 2-deoxy-2-[18F]fluoro-D-mannose positron emission tomography imaging in atherosclerosis.  Nat Med. 2014 Feb;20(2):215-9. doi: 10.1038/nm.3437. Epub 2014 Jan 12. PMID: 24412923
  9. Campbell IC, Timmins LH, Giddens DP, Virmani R, Veneziani A, Rab ST, Samady H, McDaniel MC, Finn AV, Taylor WR, Oshinski JN. Computational Fluid Dynamics Simulations of Hemodynamics in Plaque Erosion.  Cardiovasc Eng Technol. 2013 Dec;4(4). doi: 10.1007/s13239-013-0165-3. PMID: 24223678
  10. Ali ZA, Roleder T, Narula J, Mohanty BD, Baber U, Kovacic JC, Mintz GS, Otsuka F, Pan S, Virmani R, Sharma SK, Moreno P, Kini AS. Increased thin-cap neoatheroma and periprocedural myocardial infarction in drug-eluting stent restenosis: multimodality intravascular imaging of drug-eluting and bare-metal stents.  Circ Cardiovasc Interv. 2013 Oct 1;6(5):507-17. doi: 10.1161/CIRCINTERVENTIONS.112.000248. Epub 2013 Sep 24.  PMID: 24065447
  11. Otsuka F, Yahagi K, Sakakura K, Virmani R. Why is the mammary artery so special and what protects it from atherosclerosis? Ann Cardiothorac Surg. 2013 Jul;2(4):519-26. doi: 10.3978/j.issn.2225-319X.2013.07.06. PMID: 23977631
  12. Otsuka F, Sakakura K, Virmani R. Are mast cells the real culprit in atherosclerosis? Eur Heart J.  2013 PubMed PMID 23832491
  13. Portanova A, Hakakian N, Mikulis DJ, Virmani R, Abdalla WM, Wasserman BA. Intracranial vasa vasorum: insights and implications for imaging. Radiology. 2013 Jun;267(3):667-79. doi: 10.1148/radiol.13112310. Review. PMID: 23704290
  14. Otsuka F, Nakano M, Sakakura K, Ladich E, Kolodgie FD, Virmani R. Unique demands of the femoral anatomy and pathology and the need for unique interventions. J Cardiovasc Surg (Torino). 2013 Apr;54(2):191-210. Review. PMID: 23558655
  15. Najafi AH, Aghili N, Tilan JU, Andrews JA, Peng X, Lassance-Soares RM, Sood S, Alderman LO, Abe K, Li L, Kolodgie FD, Virmani R, Zukowska Z, Epstein SE, Burnett MS. A new murine model of stress-induced complex atherosclerotic lesions.  Dis Model Mech. 2013 Mar;6(2):323-31. doi: 10.1242/dmm.009977. Epub 2013 Jan 11. PMID: 23324329
  16. Schneiderman J, Schaefer K, Kolodgie FD, Savion N, Kotev-Emeth S, Dardik R, Simon AJ, Halak M, Pariente C, Engelberg I, Konstantinides S, Virmani R.
  17. Sheet D, Karamalis A, Eslami A, Noël P, Virmani R, Nakano M, Chatterjee J, Ray AK, Laine AF, Carlier SG, Navab N, Katouzian A. Hunting for necrosis in the shadows of intravascular ultrasound. Comput Med Imaging Graph. 2014 Mar;38(2):104-12. doi: 10.1016/j.compmedimag.2013.08.002. Epub 2013 Sep 2. PMID: 24035737
  18. Otsuka F, Finn AV, Virmani R. Do vulnerable and ruptured plaques hide in heavily calcified arteries? Atherosclerosis. 2013 Jul;229(1):34-7. doi:   Epub 2013 Jan 9 PMID: 23375681
  19. Tao M, Yu P, Nguyen BT, Mizrahi B, Savion N, Kolodgie FD, Virmani R, Hao S, Ozaki CK, Schneiderman J. Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):311-20. doi: 10.1161/ATVBAHA.112.300543. Epub 2012 Dec 6. PMID: 23220275
  20. Campbell IC, Weiss D, Suever JD, Virmani R, Veneziani A, Vito RP, Oshinski JN, Taylor WR. Biomechanical modeling and morphology analysis indicates plaque rupture due to mechanical failure unlikely in atherosclerosis-prone mice.  Am J Physiol Heart Circ Physiol. 2013 Feb 1;304(3):H473-86. doi: 10.1152/ajpheart.00620.2012. Epub 2012 Nov 30. PMID: 2320397
  21. Finn AV, Saeed O, Virmani R. Macrophage subsets in human atherosclerosis. Circ Res. 2012 Apr 27;110(9):e64; author reply e65-6. doi: 10.1161/CIRCRESAHA.112.268714. PMID: 22539759
  22. Schneiderman J, Schaefer K, Kolodgie FD, Savion N, Kotev-Emeth S, Dardik R, Simon AJ, Halak M, Pariente C, Engelberg I, Konstantinides S, Virmani R. Leptin locally synthesized in carotid atherosclerotic plaques could be associated with lesion instability and cerebral emboli. J Am Heart Assoc. 2012 Oct;1(5):e001727. doi: 10.1161/JAHA.112.001727. Epub 2012 Oct 25.
    PMID: 23316287
  23. Zhao HQ, Nikanorov A, Virmani R, Schwartz LB.  Inhibition of experimental neointimal hyperplasia and neoatherosclerosis by local, stent-mediated delivery of everolimus. J Vasc Surg. 2012 Dec;56(6):1680-8. doi: 10.1016/j.jvs.2012.04.022. Epub 2012 Jul 27.
  24. van Dijk RA, Kolodgie F, Ravandi A, Leibundgut G, Hu PP, Prasad A, Mahmud E, Dennis E, Curtiss LK, Witztum JL, Wasserman BA, Otsuka F, Virmani R, Tsimikas S. Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions. J Lipid Res. 2012 Dec;53(12):2773-90. doi: 10.1194/jlr.P030890. Epub 2012 Sep 11.
  25. Falk E, Nakano M, Bentzon JF, Finn AV, Virmani R. Update on acute coronary syndromes: the pathologists’ view. Eur Heart J. 2013 Mar;34(10):719-28. doi: 10.1093/eurheartj/ehs411. Epub 2012 Dec 13. Review. PMID: 23242196 Mt Sinai J Med. 2012 Nov-Dec;79(6):641-53. doi: 10.1002/msj.21353. Review. PMID: 22969153
  26. Otsuka F, Fuster V, Narula J, Virmani R. Omnipresent atherosclerotic disease: time to depart from analysis of individual vascular beds. PMID: 23239203
  27. Sakakura K, Nakano M, Otsuka F, Ladich E, Kolodgie FD, Virmani R. Pathophysiology of atherosclerosis plaque progression. Heart Lung Circ. 2013 Jun;22(6):399-411. doi: 10.1016/j.hlc.2013.03.001. Epub 2013 Mar 29. Review. Erratum in: Heart Lung Circ. 2014 Apr;23(4):387. PMID: 23541627
  28. Malle C, Tada T, Steigerwald K, Ughi GJ, Schuster T, Nakano M, Massberg S, Jehle J, Guagliumi G, Kastrati A, Virmani R, Byrne RA, Joner M.  Tissue characterization after drug-eluting stent implantation using optical coherence tomography. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1376-83. doi: 10.1161/ATVBAHA.113.301227. Epub 2013 Mar 28. PMID: 23539216
  29. Yazdani SK, Farb A, Nakano M, Vorpahl M, Ladich E, Finn AV, Kolodgie FD, Virmani R. Pathology of drug-eluting versus bare-metal stents in saphenous vein bypass graft lesions.  JACC Cardiovasc Interv. 2012 Jun;5(6):666-74. doi: 10.1016/j.jcin.2011.12.017 PMID: 22721663
  30. Joner M, Virmani R. Glagov’s phenomenon: has our understanding of vascular remodeling changed?  Coron Artery Dis.  2014.  PubMed PMID 24492456
  31. Otsuka F, Sakakura K, Yahagi K, Joner M, Virmani R. Has our understanding of calcification in human coronary atherosclerosis progressed? Arterioscler Thromb Vasc Biol.  2014 PubMed PMID:24558104
  32. Seifarth H, Schlett CL, Nakano M, Otsuka F, Károlyi M, Liew G, Maurovich-Horvat P, Alkadhi H, Virmani R, Hoffmann U. Histopathological correlates of the napkin-ring sign plaque in coronary CT angiography. Atherosclerosis. 2012 Sep;224(1):90-6. doi: 10.1016/j.atherosclerosis.2012.06.021. Epub 2012 Jun 21. PMID: 22771191
  33. Bentzon JF, Otsuka F, Virmani R, Falk E.  Mechanisms of plaque formation and rupture. Circ Res.  2014 PubMed PMID 24902970
  34. Yazdani SK, Otsuka F, Nakano M, Finn AV, Virmani R.  Do animal models of vein graft atherosclerosis predict outcomes in man?  Atherosclerosis. 2012 Jul;223(1):102-5. doi: 10.1016/j.atherosclerosis.2012.04.028. Epub 2012 May 12 PMID: 22658552
  35. Tearney GJ, Regar E, Akasaka T, Adriaenssens T, Barlis P, Bezerra HG, Bouma B, Bruining N, Cho JM, Chowdhary S, Costa MA, de Silva R, Dijkstra J, Di Mario C, Dudek D, Falk E, Feldman MD, Fitzgerald P, Garcia-Garcia HM, Gonzalo N, Granada JF, Guagliumi G, Holm NR, Honda Y, Ikeno F, Kawasaki M, Kochman J, Koltowski L, Kubo T, Kume T, Kyono H, Lam CC, Lamouche G, Lee DP, Leon MB, Maehara A, Manfrini O, Mintz GS, Mizuno K, Morel MA, Nadkarni S, Okura H, Otake H, Pietrasik A, Prati F, Räber L, Radu MD, Rieber J, Riga M, Rollins A, Rosenberg M, Sirbu V, Serruys PW, Shimada K, Shinke T, Shite J, Siegel E, Sonoda S, Suter M, Takarada S, Tanaka A, Terashima M, Thim T, Uemura S, Ughi GJ, van Beusekom HM, van der Steen AF, van Es GA, van Soest G, Virmani R, Waxman S, Weissman NJ, Weisz G; International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT).  Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation. J Am Coll Cardiol. 2012 Mar 20;59(12):1058-72. doi: 10.1016/j.jacc.2011.09.079. Erratum in: J Am Coll Cardiol. 2012 May 1;59(18):1662. Dudeck, Darius [corrected to Dudek, Darius]; Falk, Erlin [corrected to Falk, Erling]; Garcia, Hector [corrected to Garcia-Garcia, Hector M]; Sonada, Shinjo [corrected to Sonoda, Shinjo]; Troels, Thim [corrected to Thim, Troels]; van Es, Gerrit-Ann [corrected to van Es, Gerrit-Anne].  PMID: 22421299
  36. Nakano M, Vorpahl M, Otsuka F, Taniwaki M, Yazdani SK, Finn AV, Ladich ER, Kolodgie FD, Virmani R. Ex vivo assessment of vascular response to coronary stents by optical frequency domain imaging. JACC Cardiovasc Imaging. 2012 Jan;5(1):71-82. doi: 10.1016/j.jcmg.2011.09.015. PMID: 22239896
  37. Maehara A, Cristea E, Mintz GS, Lansky AJ, Dressler O, Biro S, Templin B, Virmani R, de Bruyne B, Serruys PW, Stone GW. Definitions and methodology for the grayscale and radiofrequency intravascular ultrasound and coronary angiographic analyses. JACC Cardiovasc Imaging. 2012 Mar;5(3 Suppl):S1-9. doi: 10.1016/j.jcmg.2011.11.019. PMID: 22421222
  38. Nakano M, Otsuka F, Virmani R. Letter by Nakano et Al regarding article, “optical coherence tomographic analysis of in-stent neoatherosclerosis after drug-eluting stent implantation”.  Circulation. 2011 Dec 20;124(25):e954; author reply e955. doi: 10.1161/CIRCULATIONAHA.111.048736. No abstract available. PMID: 22184050
  39. Otsuka F, Joner M, Prati F, Virmani R, Narula J. Clinical classification of plaque morphology in coronary disease. Nat Rev Cardiol.  2014 PubMed PMID 24776706
  40. Virmani R, Joner M, Sakakura K. Recent highlights of ATVB: clarification. Arterioscler Thromb Vasc Biol.  2014 PubMed PMID:24876349
  41. Finn AV, Nakano M, Polavarapu R, Karmali V, Saeed O, Zhao X, Yazdani S, Otsuka F, Davis T, Habib A, Narula J, Kolodgie FD, Virmani R.
    Hemoglobin directs macrophage differentiation and prevents foam cell formation in human atherosclerotic plaques.  J Am Coll Cardiol. 2012 Jan 10;59(2):166-77. doi: 10.1016/j.jacc.2011.10.852. Epub 2011 Dec 9. PMID: 22154776
  42. Waksman R, Pakala R, Baffour R, Seabron R, Hellinga D, Chan R, Su SH, Kolodgie F, Virmani R. In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries. Catheter Cardiovasc Interv. 2012 Sep 1;80(3):429-36. doi: 10.1002/ccd.23407. Epub 2011 Dec 1. PMID: 22105925
  43. Guagliumi G, Capodanno D, Saia F, Musumeci G, Tarantini G, Garbo R, Tumminello G, Sirbu V, Coccato M, Fineschi M, Trani C, De Benedictis M, Limbruno U, De Luca L, Niccoli G, Bezerra H, Ladich E, Mechanisms of atherothrombosis and vascular response to primary percutaneous coronary intervention in women versus men with acute myocardial infarction: results of the OCTAVIA study. JACC Cardiovasc Interv.  2014. PubMed PMID:25129664
  44. Killer-Oberpfalzer M, Aichholzer M, Weis S, Richling B, Jones R, Virmani R, Cruise GM. Histological analysis of clipped human intracranial aneurysms and parent arteries with short-term follow-up. Cardiovasc Pathol. 2012 Jul-Aug;21(4):299-306. doi: 10.1016/j.carpath.2011.09.010. Epub 2011 Nov 18. PMID: 22100991
  45. Saeed O, Otsuka F, Polavarapu R, Karmali V, Weiss D, Davis T, Rostad B, Pachura K, Adams L, Elliott J, Taylor WR, Narula J, Kolodgie F, Virmani R, Hong CC, Finn AV  Pharmacological suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):299-307. doi: 10.1161/ATVBAHA.111.240101. Epub 2011 Nov 17. PMID: 22095982
  46. Donnelly P, Maurovich-Horvat P, Vorpahl M, Nakano M, Kaple RK, Warger W, Tanaka A, Tearney G, Virmani R, Hoffmann U.  Multimodality imaging atlas of coronary atherosclerosis.  JACC Cardiovasc Imaging. 2010 Aug;3(8):876-80. doi: 10.1016/j.jcmg.2010.06.006. No abstract available. PMID: 20705270
  47. Olive M, Harten I, Mitchell R, Beers JK, Djabali K, Cao K, Erdos MR, Blair C, Funke B, Smoot L, Gerhard-Herman M, Machan JT, Kutys R, Virmani R, Collins FS, Wight TN, Nabel EG, Gordon LB.  Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2301-9. doi: 10.1161/ATVBAHA.110.209460. Epub 2010 Aug 26.
    Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.  Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2301-9. doi: 10.1161/ATVBAHA.110.209460. Epub 2010 Aug 26. PMID: 20798379
  48. Singh PP, Abbott JD, Lombardero MS, Sutton-Tyrrell K, Woodhead G, Venkitachalam L, Tsapatsaris NP, Piemonte TC, Lago RM, Rutter MK, Nesto RW; Bypass Angioplasty Revascularization Investigation 2 Diabetes Study Group. The prevalence and predictors of an abnormal ankle-brachial index in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. Diabetes Care. 2011 Feb;34(2):464-7. doi: 10.2337/dc10-1734. PMID: 21270200
  49. Rudd JH, Narula J, Strauss HW, Virmani R, Machac J, Klimas M, Tahara N, Fuster V, Warburton EA, Fayad ZA, Tawakol AA.    Imaging atherosclerotic plaque inflammation by fluorodeoxyglucose with positron emission tomography: ready for prime time?    J Am Coll Cardiol. 2010 Jun 8;55(23):2527-35. doi: 10.1016/j.jacc.2009.12.061. Review. PMID: 20513592
  50. Nakazawa G, Yazdani SK, Finn AV, Vorpahl M, Kolodgie FD, Virmani R.  Pathological findings at bifurcation lesions: the impact of flow distribution on atherosclerosis and arterial healing after stent implantation. J Am Coll Cardiol. 2010 Apr 20;55(16):1679-87. doi: 10.1016/j.jacc.2010.01.021.PMID: 20394871
  51. Alfieri O, Mayosi BM, Park SJ, Sarrafzadegan N, Virmani R. Exploring unknowns in cardiology. Nat Rev Cardiol.  2014 PubMed PMID:25245833
  52. Ladich E, Nakano M, Carter-Monroe N, Virmani R Pathology of calcific aortic stenosis. Future Cardiol. 2011 Sep;7(5):629-42. doi: 10.2217/fca.11.53. Review. PMID: 21929343 Evaluation of polymer-based comparator drug-eluting stents using a rabbit model of iliac artery atherosclerosis. Circ Cardiovasc Interv. 2011 Feb 1;4(1):38-46. doi: 10.1161/CIRCINTERVENTIONS.110.957654. Epub 2011 Jan 4. PMID: 21205943
  53. van Dijk RA, Virmani R, von der Thüsen JH, Schaapherder AF, Lindeman JH.  The natural history of aortic atherosclerosis: a systematic histopathological evaluation of the peri-renal region. Atherosclerosis. 2010 May;210(1):100-6. doi: 10.1016/j.atherosclerosis.2009.11.016. Epub 2009 Nov 26. PMID: 20031134
  54. Finn AV, Kolodgie FD, Virmani R   Correlation between carotid intimal/medial thickness and atherosclerosis: a point of view from pathology. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):177-81. doi: 10.1161/ATVBAHA.108.173609. Epub 2009 Aug 13. Review.  PMID: 19679833
  55. Haider N, Hartung D, Fujimoto S, Petrov A, Kolodgie FD, Virmani R, Ohshima S, Liu H, Zhou J, Fujimoto A, Tahara A, Hofstra L, Narula N, Reutelingsperger C, Narula J.  Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis. J Nucl Cardiol. 2009 Sep-Oct;16(5):753-62. doi: 10.1007/s12350-009-9107-8. Epub 2009 Aug 7.  PMID: 19662466
  56. Finn AV, Kramer MC, Vorpahl M, Kolodgie FD, Virmani R Pharmacotherapy of coronary atherosclerosis. Expert Opin Pharmacother. 2009 Jul;10(10):1587-603. doi: 10.1517/14656560902988494. Review. PMID: 19527187
  57. Fu Z, Wang M, Gucek M, Zhang J, Wu J, Jiang L, Monticone RE, Khazan B, Telljohann R, Mattison J, Sheng S, Cole RN, Spinetti G, Pintus G, Liu L, Kolodgie FD, Virmani R, Spurgeon H, Ingram DK, Everett AD, Lakatta EG, Van Eyk JE.  Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion. Circ Res. 2009 Jun 19;104(12):1337-46. doi: 10.1161/CIRCRESAHA.108.187088. Epub 2009 May 14. PMID: 19443842
  58. Motoyama S, Sarai M, Harigaya H, Anno H, Inoue K, Hara T, Naruse H, Ishii J, Hishida H, Wong ND, Virmani R, Kondo T, Ozaki Y, Narula J.  Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome.  J Am Coll Cardiol. 2009 Jun 30;54(1):49-57. doi: 10.1016/j.jacc.2009.02.068. PMID: 19555840
  59. Mauriello A, Sangiorgi GM, Virmani R, Trimarchi S, Holmes DR Jr, Kolodgie FD, Piepgras DG, Piperno G, Liotti D, Narula J, Righini P, Ippoliti A, Spagnoli LG   A pathobiologic link between risk factors profile and morphological markers of carotid instability. Atherosclerosis. 2010 Feb;208(2):572-80. doi: 10.1016/j.atherosclerosis.2009.07.048. Epub 2009 Aug 3 PMID: 19683236
  60. Nakazawa G, Vorpahl M, Finn AV, Narula J, Virmani R One step forward and two steps back with drug-eluting-stents: from preventing restenosis to causing late thrombosis and nouveau atherosclerosis.  JACC Cardiovasc Imaging. 2009 May;2(5):625-8. doi: 10.1016/j.jcmg.2009.01.011 PMID: 19442951
  61. Sluimer JC, Kolodgie FD, Bijnens AP, Maxfield K, Pacheco E, Kutys B, Duimel H, Frederik PM, van Hinsbergh VW, Virmani R, Daemen MJ.  Thin-walled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions relevance of compromised structural integrity for intraplaque microvascular leakage. J Am Coll Cardiol. 2009 Apr 28;53(17):1517-27. doi: 10.1016/j.jacc.2008.12.056.  PMID: 19389562
  62. Waksman R, Baffour R, Pakala R, Scheinowitz M, Hellinga D, Seabron R, Chan R, Kolodgie F, Virmani R .  Effects of exogenous peripheral-blood-derived endothelial progenitor cells or unfractionated bone-marrow-derived cells on neointimal formation and inflammation in cholesterol-fed, balloon-denuded, and radiated iliac arteries of inbred rabbits.  Cardiovasc Revasc Med. 2009 Apr-Jun;10(2):110-6. doi: 10.1016/j.carrev.2009.02.001. PMID: 19327673
  63. Tahara N, Imaizumi T, Virmani R, Narula J.  Clinical feasibility of molecular imaging of plaque inflammation in atherosclerosis.   J Nucl Med. 2009 Mar;50(3):331-4. doi: 10.2967/jnumed.108.060376. Epub 2009 Feb 17. Review.  PMID: 19223412
  64. Nakazawa G, Finn AV, Ladich E, Ribichini F, Coleman L, Kolodgie FD, Virmani R.  Drug-eluting stent safety: findings from preclinical studies. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1379-91. doi: 10.1586/14779072.6.10.1379. Review.  PMID: 19018691
  65. Waksman R, McEwan PE, Moore TI, Pakala R, Kolodgie FD, Hellinga DG, Seabron RC, Rychnovsky SJ, Vasek J, Scott RW, Virmani R.  PhotoPoint photodynamic therapy promotes stabilization of atherosclerotic plaques and inhibits plaque progression.  J Am Coll Cardiol. 2008 Sep 16;52(12):1024-32. doi: 10.1016/j.jacc.2008.06.023. PMID: 18786486
  66. Joner M, Morimoto K, Kasukawa H, Steigerwald K, Merl S, Nakazawa G, John MC, Finn AV, Acampado E, Kolodgie FD, Gold HK, Virmani R.  Site-specific targeting of nanoparticle prednisolone reduces in-stent restenosis in a rabbit model of established atheroma. Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):1960-6. doi: 10.1161/ATVBAHA.108.170662. Epub 2008 Aug 7. PMID: 18688017
  67. Narula J, Garg P, Achenbach S, Motoyama S, Virmani R, Strauss HW.    Arithmetic of vulnerable plaques for noninvasive imaging.  Nat Clin Pract Cardiovasc Med. 2008 Aug;5 Suppl 2:S2-10. doi: 10.1038/ncpcardio1247. Review. PMID: 18641603
  68. Xu C, Schmitt JM, Carlier SG, Virmani R.  Characterization of atherosclerosis plaques by measuring both backscattering and attenuation coefficients in optical coherence tomography. J Biomed Opt. 2008 May-Jun;13(3):034003. doi: 10.1117/1.2927464. PMID: 18601548
  69.  König A, Margolis MP, Virmani R, Holmes D, Klauss V.  Technology insight: in vivo coronary plaque classification by intravascular ultrasonography radiofrequency analysis. Nat Clin Pract Cardiovasc Med. 2008 Apr;5(4):219-29. doi: 10.1038/ncpcardio1123. Epub 2008 Feb 26. Review. PMID: 18301388
  70. Lim WS, Timmins JM, Seimon TA, Sadler A, Kolodgie FD, Virmani R, Tabas I. Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. Circulation. 2008 Feb 19;117(7):940-51. doi: 10.1161/CIRCULATIONAHA.107.711275. Epub 2008 Jan 28. Erratum in: Circulation. 2008 Apr 1;117(13):e303 PMID: 18227389
  71. Sarai M, Hartung D, Petrov A, Zhou J, Narula N, Hofstra L, Kolodgie F, Isobe S, Fujimoto S, Vanderheyden JL, Virmani R, Reutelingsperger C, Wong ND, Gupta S, Narula J. Broad and specific caspase inhibitor-induced acute repression of apoptosis in atherosclerotic lesions evaluated by radiolabeled annexin A5 imaging. J Am Coll Cardiol. 2007 Dec 11;50(24):2305-12. Epub 2007 Nov 26. PMID: 18068039
  72. Hartung D, Petrov A, Haider N, Fujimoto S, Blankenberg F, Fujimoto A, Virmani R, Kolodgie FD, Strauss HW, Narula J.  Radiolabeled Monocyte Chemotactic Protein 1 for the detection of inflammation in experimental atherosclerosis. J Nucl Med. 2007 Nov;48(11):1816-21. Epub 2007 Oct 17. PMID: 17942805
  73. Kolodgie FD, Nakazawa G, Sangiorgi G, Ladich E, Burke AP, Virmani R.  Pathology of atherosclerosis and stenting. Neuroimaging Clin N Am. 2007 Aug;17(3):285-301, vii. Review. PMID: 17826632
  74. Cheruvu PK, Finn AV, Gardner C, Caplan J, Goldstein J, Stone GW, Virmani R, Muller JE. Frequency and distribution of thin-cap fibroatheroma and ruptured plaques in human coronary arteries: a pathologic study. J Am Coll Cardiol. 2007 Sep 4;50(10):940-9. Epub 2007 Aug 20. PMID: 17765120
  75. Burke AP, Virmani R. Pathophysiology of acute myocardial infarction. Med Clin North Am. 2007 Jul;91(4):553-72; ix. Review. PMID: 17640536
  76. Ribichini F, Joner M, Ferrero V, Finn AV, Crimins J, Nakazawa G, Acampado E, Kolodgie FD, Vassanelli C, Virmani R. Effects of oral prednisone after stenting in a rabbit model of established atherosclerosis. J Am Coll Cardiol. 2007 Jul 10;50(2):176-85. Epub 2007 Jun 22. PMID: 1761630
  77. Hartung D, Schäfers M, Fujimoto S, Levkau B, Narula N, Kopka K, Virmani R, Reutelingsperger C, Hofstra L, Kolodgie FD, Petrov A, Narula J. Targeting of matrix metalloproteinase activation for noninvasive detection of vulnerable atherosclerotic lesions. Eur J Nucl Med Mol Imaging. 2007 Jun;34 Suppl 1:S1-8. Review. PMID: 17497106
  78. Wang M, Zhang J, Jiang LQ, Spinetti G, Pintus G, Monticone R, Kolodgie FD, Virmani R, Lakatta EG.  Proinflammatory profile within the grossly normal aged human aortic wall. Hypertension. 2007 Jul;50(1):219-27. Epub 2007 Apr 23. PMID: 17452499
  79. Hara H, Pedersen WR, Ladich E, Mooney M, Virmani R, Nakamura M, Feldman T, Schwartz RS.  Percutaneous balloon aortic valvuloplasty revisited: time for a renaissance? Circulation. 2007 Mar 27;115(12):e334-8. Review. No abstract available. PMID: 17389271
  80. Joner M, Farb A, Cheng Q, Finn AV, Acampado E, Burke AP, Skorija K, Creighton W, Kolodgie FD, Gold HK, Virmani R   Pioglitazone inhibits in-stent restenosis in atherosclerotic rabbits by targeting transforming growth factor-beta and MCP-1. Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):182-9. Epub 2006 Oct 26. PMID: 17068283
  81. Virmani R, Ladich ER, Burke AP, Kolodgie FD.  Histopathology of carotid atherosclerotic disease. Neurosurgery. 2006 Nov;59(5 Suppl 3):S219-27; discussion S3-13. Review. PMID: 17053606
  82. Vengrenyuk Y, Carlier S, Xanthos S, Cardoso L, Ganatos P, Virmani R, Einav S, Gilchrist L, Weinbaum S. A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14678-83. Epub 2006 Sep 26. PMID: 17003118
  83. Kolodgie FD, Burke AP, Skorija KS, Ladich E, Kutys R, Makuria AT, Virmani R.  Lipoprotein-associated phospholipase A2 protein expression in the natural progression of human coronary atherosclerosis. Arterioscler Thromb Vasc Biol. 2006 Nov;26(11):2523-9. Epub 2006 Sep 7. PMID: 16960105
  84. Isobe S, Tsimikas S, Zhou J, Fujimoto S, Sarai M, Branks MJ, Fujimoto A, Hofstra L, Reutelingsperger CP, Murohara T, Virmani R, Kolodgie FD, Narula N, Petrov A, Narula J.  Noninvasive imaging of atherosclerotic lesions in apolipoprotein E-deficient and low-density-lipoprotein receptor-deficient mice with annexin A5. J Nucl Med. 2006 Sep;47(9):1497-505 PMID: 16954559
  85. Verhoeven BA, Moll FL, Koekkoek JA, van der Wal AC, de Kleijn DP, de Vries JP, Verheijen JH, Velema E, Busser E, Schoneveld A, Virmani R, Pasterkamp G   Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy. Stroke. 2006 Aug;37(8):2054-60. Epub 2006 Jun 29. PMID: 16809559
  86. Virmani R, Burke AP, Farb A, Kolodgie FD.  Pathology of the vulnerable plaque. J Am Coll Cardiol. 2006 Apr 18;47(8 Suppl):C13-8. PMID: 16631505
  87. Stefanadis C, Toutouzas K, Stefanadi E, Kolodgie F, Virmani R, Kipshidze N. First experimental application of bevacizumab-eluting PC coated stent for inhibition of vasa vasorum of atherosclerotic plaque: angiographic results in a rabbit atheromatic model. Hellenic J Cardiol. 2006 Jan-Feb;47(1):7-10. PMID: 16532709
  88. Joner M, Nakazawa G, Bonsignore C, Acampado E, Steigerwald K, Merl S, Vallbracht T, Kolodgie FD, Virmani R.  Histopathologic evaluation of nitinol self-expanding stents in an animal model of advanced atherosclerotic lesions.  EuroIntervention. 2010 Jan;5(6):737-44.  PMID: 20142227
  89. Ladich E, Virmani R, Burke A. Sudden cardiac death not related to coronary atherosclerosis. Toxicol Pathol. 2006;34(1):52-7. Review. PMID: 16507544
  90. Virmani R, Burke AP, Kolodgie F. Morphological characteristics of coronary atherosclerosis in diabetes mellitus. Can J Cardiol. 2006 Feb;22 Suppl B:81B-84B. Review. PMID: 16498517
  91. Hartung D, Sarai M, Petrov A, Kolodgie F, Narula N, Verjans J, Virmani R, Reutelingsperger C, Hofstra L, Narula J.  Resolution of apoptosis in atherosclerotic plaque by dietary modification and statin therapy.  J Nucl Med. 2005 Dec;46(12):2051-6. PMID: 16330569
  92. Wasserman BA, Wityk RJ, Trout HH 3rd, Virmani R Low-grade carotid stenosis: looking beyond the lumen with MRI. Stroke. 2005 Nov;36(11):2504-13. Epub 2005 Oct 20. Review. PMID: 16239630
  93. van Oostrom O, Velema E, Schoneveld AH, de Vries JP, de Bruin P, Seldenrijk CA, de Kleijn DP, Busser E, Moll FL, Verheijen JH, Virmani R, Pasterkamp G.  Age-related changes in plaque composition: a study in patients suffering from carotid artery stenosis. Cardiovasc Pathol. 2005 May-Jun;14(3):126-34. PMID: 15914297
  94. Virmani R, Kolodgie FD, Farb A.  Drug-eluting stents: are they really safe? Am Heart Hosp J. 2004 Spring;2(2):85-8. PMID: 15604849
  95. Schwartz RS, Chronos NA, Virmani R.Preclinical restenosis models and drug-eluting stents: still important, still much to learn. J Am Coll Cardiol. 2004 Oct 6;44(7):1373-85. Review.  PMID: 15464316
  96.  Burke AP, Kolodgie FD, Zieske A, Fowler DR, Weber DK, Varghese PJ, Farb A, Virmani R. Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study. Arterioscler Thromb Vasc Biol. 2004 Jul;24(7):1266-71. Epub 2004 May 13. PMID: 15142859
  97. Kolodgie FD, Gold HK, Burke AP, Fowler DR, Kruth HS, Weber DK, Farb A, Guerrero LJ, Hayase M, Kutys R, Narula J, Finn AV, Virmani R. Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med. 2003 Dec 11;349(24):2316-25.  PMID: 14668457
  98. Burke AP, Virmani R, Galis Z, Haudenschild CC, Muller JE. 34th Bethesda Conference: Task force #2–What is the pathologic basis for new atherosclerosis imaging techniques? J Am Coll Cardiol. 2003 Jun 4;41(11):1874-86. Review. No abstract available. Erratum in: J Am Coll Cardiol. 2003 Sep 17;42(6):1147.  PMID: 12798554
  99. Burke AP, Fonseca V, Kolodgie F, Zieske A, Fink L, Virmani R. Increased serum homocysteine and sudden death resulting from coronary atherosclerosis with fibrous plaques. Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1936-41. Erratum in: Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):705. PMID: 12426228
  100. Burke AP, Tracy RP, Kolodgie F, Malcom GT, Zieske A, Kutys R, Pestaner J, Smialek J, Virmani R  Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies. Circulation. 2002 Apr 30;105(17):2019-23 PMID: 11980679
  101. Virmani R, Farb A, Kolodgie FD.  Histopathologic alterations after endovascular radiation and antiproliferative stents: similarities and differences. Herz. 2002 Feb;27(1):1-6. Review. PMID: 11951791
  102. Burke AP, Farb A, Pestaner J, Malcom GT, Zieske A, Kutys R, Smialek J, Virmani R. Traditional risk factors and the incidence of sudden coronary death with and without coronary thrombosis in blacks. Circulation. 2002 Jan 29;105(4):419-24. PMID: 11815422
  103. Burke AP, Kolodgie FD, Farb A, Weber D, Virmani R. Morphological predictors of arterial remodeling in coronary atherosclerosis. Circulation. 2002 Jan 22;105(3):297-303. PMID: 11804983
  104. Kolodgie FD, Narula J, Haider N, Virmani R.  Apoptosis in atherosclerosis. Does it contribute to plaque instability? Cardiol Clin. 2001 Feb;19(1):127-39, ix. Review. PMID: 11787806
  105. Virmani R, Burke AP, Farb A.  Sudden cardiac death. Cardiovasc Pathol. 2001 Sep-Oct;10(5):211-8. Review. PMID: 11673058
  106. Bayes-Genis A, Conover CA, Overgaard MT, Bailey KR, Christiansen M, Holmes DR Jr, Virmani R, Oxvig C, Schwartz RS.  Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med. 2001 Oct 4;345(14):1022-9. PMID: 11586954
  107. Burke AP, Weber DK, Kolodgie FD, Farb A, Taylor AJ, Virmani R. Pathophysiology of calcium deposition in coronary arteries. Herz. 2001 Jun;26(4):239-44. Review. PMID: 11479935
  108. Virmani R, Farb A, Carter AJ, Jones RM. Pathology of radiation-induced coronary artery disease in human and pig. Cardiovasc Radiat Med. 1999 Jan-Mar;1(1):98-101. Review. PMID: 11272363
  109. Schmermund A, Schwartz RS, Adamzik M, Sangiorgi G, Pfeifer EA, Rumberger JA, Burke AP, Farb A, Virmani R. Coronary atherosclerosis in unheralded sudden coronary death under age 50: histo-pathologic comparison with ‘healthy’ subjects dying out of hospital. Atherosclerosis. 2001 Apr;155(2):499-508. PMID: 11254922
  110. Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P.  Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.  Am J Pathol. 2001 Mar;158(3):879-91.  PMID: 11238037
  111. Burke AP, Kolodgie FD, Farb A, Weber DK, Malcom GT, Smialek J, Virmani R.  Healed plaque ruptures and sudden coronary death: evidence that subclinical rupture has a role in plaque progression. Circulation. 2001 Feb 20;103(7):934-40. PMID: 11181466
  112. Burke AP, Farb A, Malcom G, Virmani R.  Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis.   Am Heart J. 2001 Feb;141(2 Suppl):S58-62. PMID: 11174360
  113. Schwartz SM, Virmani R, Rosenfeld ME.  The good smooth muscle cells in atherosclerosis.   Curr Atheroscler Rep. 2000 Sep;2(5):422-9. Review. PMID: 11122774
  114. Rosenfeld ME, Polinsky P, Virmani R, Kauser K, Rubanyi G, Schwartz SM Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse. Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2587-92. PMID: 11116057
  115. Burke AP, Taylor A, Farb A, Malcom GT, Virmani R.  Coronary calcification: insights from sudden coronary death victims. Z Kardiol. 2000;89 Suppl 2:49-53. PMID: 10769403
  116. Carter AJ, Farb A, Gould KE, Taylor AJ, Virmani R   The degree of neointimal formation after stent placement in atherosclerotic rabbit iliac arteries is dependent on the underlying plaque. Cardiovasc Pathol. 1999 Mar-Apr;8(2):73-80. PMID: 10724504
  117. Mauriello A, Sangiorgi G, Palmieri G, Virmani R, Holmes DR Jr, Schwartz RS, Pistolese R, Ippoliti A, Spagnoli LG.  Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks. Circulation. 2000 Feb 22;101(7):744-50. PMID: 10683347
  118. Schneider DB, Vassalli G, Wen S, Driscoll RM, Sassani AB, DeYoung MB, Linnemann R, Virmani R, Dichek DA. Expression of Fas ligand in arteries of hypercholesterolemic rabbits accelerates atherosclerotic lesion formation. Arterioscler Thromb Vasc Biol. 2000 Feb;20(2):298-308. PMID: 10669624
  119. Taylor AJ, Burke AP, Farb A, Yousefi P, Malcom GT, Smialek J, Virmani R.  Arterial remodeling in the left coronary system: the role of high-density lipoprotein cholesterol. J Am Coll Cardiol. 1999 Sep;34(3):760-7. PMID: 10483958
  120. Virmani R, Farb A, Carter AJ, Jones RM.  Comparative pathology: radiation-induced coronary artery disease in man and animals. Semin Interv Cardiol. 1998 Sep-Dec;3(3-4):163-72. Review. PMID: 10406688
  121. Virmani R, Burke AP, Farb A, Kark JA. Causes of sudden death in young and middle-aged competitive athletes. Cardiol Clin. 1997 Aug;15(3):439-66. Review. PMID: 9276168
  122. Antonov AS, Munn DH, Kolodgie FD, Virmani R, Gerrity RG. Aortic endothelial cells regulate proliferation of human monocytes in vitro via a mechanism synergistic with macrophage colony-stimulating factor. Convergence at the cyclin E/p27(Kip1) regulatory checkpoint. J Clin Invest. 1997 Jun 15;99(12):2867-76. PMID: 9185509
  123. Kolodgie FD, Katocs AS Jr, Largis EE, Wrenn SM, Cornhill JF, Herderick EE, Lee SJ, Virmani R.  Hypercholesterolemia in the rabbit induced by feeding graded amounts of low-level cholesterol. Methodological considerations regarding individual variability in response to dietary cholesterol and development of lesion type. Arterioscler Thromb Vasc Biol. 1996 Dec;16(12):1454-64. PMID: 8977449
  124. Marczin N, Antonov A, Papapetropoulos A, Munn DH, Virmani R, Kolodgie FD, Gerrity R, Catravas JD.  Monocyte-induced downregulation of nitric oxide synthase in cultured aortic endothelial cells. Arterioscler Thromb Vasc Biol. 1996 Sep;16(9):1095-103. PMID: 8792762
  125. Litovsky SH, Farb A, Burke AP, Rabin IY, Herderick EE, Cornhill JF, Smialek J, Virmani R.  Effect of age, race, body surface area, heart weight and atherosclerosis on coronary artery dimensions in young males. Atherosclerosis. 1996 Jun;123(1-2):243-50. PMID: 8782855
  126.  Carter AJ, Laird JR, Kufs WM, Bailey L, Hoopes TG, Reeves T, Farb A, Virmani R  Coronary stenting with a novel stainless steel balloon-expandable stent: determinants of neointimal formation and changes in arterial geometry after placement in an atherosclerotic model. J Am Coll Cardiol. 1996 Apr;27(5):1270-7. PMID: 8609355
  127. Alving CR, Swartz GM Jr, Wassef NM, Ribas JL, Herderick EE, Virmani R, Kolodgie FD, Matyas GR, Cornhill JF.  Immunization with cholesterol-rich liposomes induces anti-cholesterol antibodies and reduces diet-induced hypercholesterolemia and plaque formation. J Lab Clin Med. 1996 Jan;127(1):40-9. PMID: 8592095
  128. Farb A, Tang AL, Burke AP, Sessums L, Liang Y, Virmani R.  Sudden coronary death. Frequency of active coronary lesions, inactive coronary lesions, and myocardial infarction.   Circulation. 1995 Oct 1;92(7):1701-9. PMID: 7671351
  129. Duflou J, Virmani R, Rabin I, Burke A, Farb A, Smialek J.  Sudden death as a result of heart disease in morbid obesity. Am Heart J. 1995 Aug;130(2):306-13. PMID: 7631612
  130.  Farb A, Roberts DK, Pichard AD, Kent KM, Virmani R.  Coronary artery morphologic features after coronary rotational atherectomy: insights into mechanisms of lumen enlargement and embolization. Am Heart J. 1995 Jun;129(6):1058-67. PMID: 7754934
  131. Atkinson JB, Harlan CW, Harlan GC, Virmani R. The association of mast cells and atherosclerosis: a morphologic study of early atherosclerotic lesions in young people.   Hum Pathol. 1994 Feb;25(2):154-9. PMID: 7726878
  132. Virmani R, Farb A, Burke AP.  Coronary angioplasty from the perspective of atherosclerotic plaque: morphologic predictors of immediate success and restenosis. Am Heart J. 1994 Jan;127(1):163-79. Review. PMID: 8273736
  133. Burke AP, Farb A, Sessums L, Virmani R. Causes of sudden cardiac death in patients with replacement valves: an autopsy study. J Heart Valve Dis. 1994 Jan;3(1):10-6. PMID: 8162204
  134. Kolodgie FD, Wilson PS, Cornhill JF, Herderick EE, Mergner WJ, Virmani R. Increased prevalence of aortic fatty streaks in cholesterol-fed rabbits administered intravenous cocaine: the role of vascular endothelium. Toxicol Pathol. 1993 Sep-Oct;21(5):425-35. PMID: 8115819
  135. Kolodgie FD, Virmani R, Cornhill JF, Herderick EE, Malcom GT, Mergner WJ.  Cocaine: an independent risk factor for aortic sudanophilia. A preliminary report. Atherosclerosis. 1992 Nov;97(1):53-62. PMID: 1280144
  136. Burke AP, Farb A, Virmani R.  Causes of sudden death in athletes. Cardiol Clin. 1992 May;10(2):303-17. Review. PMID: 1533567
  137. Virmani R, Avolio AP, Mergner WJ, Robinowitz M, Herderick EE, Cornhill JF, Guo SY, Liu TH, Ou DY, O’Rourke M.  Effect of aging on aortic morphology in populations with high and low prevalence of hypertension and atherosclerosis. Comparison between occidental and Chinese communities. Am J Pathol. 1991 Nov;139(5):1119-29. PMID: 1951629
  138. Kolodgie FD, Virmani R, Cornhill JF, Herderick EE, Smialek J.  Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis. J Am Coll Cardiol. 1991 Jun;17(7):1553-60. PMID: 2033185
  139. Burke AP, Farb A, Virmani R, Goodin J, Smialek JE.  Sports-related and non-sports-related sudden cardiac death in young adults. Am Heart J. 1991 Feb;121(2 Pt 1):568-75. PMID: 1825009
  140. Virmani R.  Cocaine-associated cardiovascular disease: clinical and pathological aspects. NIDA Res Monogr. 1991;108:220-9. Review. PMID: 1749414
  141. Kolodgie FD, Virmani R, Rice HE, Mergner WJ.  Vascular reactivity during the progression of atherosclerotic plaque. A study in Watanabe heritable hyperlipidemic rabbits. Circ Res. 1990 Apr;66(4):1112-26. PMID: 2317889
  142. Virmani R, Robinowitz M, Smialek JE, Smyth DF.  Cardiovascular effects of cocaine: an autopsy study of 40 patients. Am Heart J. 1988 May;115(5):1068-76.  PMID: 3364339
  143. Shelton ME, Forman MB, Virmani R, Bajaj A, Stoney WS, Atkinson JB. A comparison of morphologic and angiographic findings in long-term internal mammary artery and saphenous vein bypass grafts. J Am Coll Cardiol. 1988 Feb;11(2):297-307. PMID: 2892871
  144. Virmani R, Robinowitz M, Geer JC, Breslin PP, Beyer JC, McAllister HA.  Coronary artery atherosclerosis revisited in Korean war combat casualties. Arch Pathol Lab Med. 1987 Oct;111(10):972-6. PMID: 3307684
  145. Clagett GP, Robinowitz M, Youkey JR, Fisher DF Jr, Fry RE, Myers SI, Lee EL, Collins GJ Jr, Virmani R  Morphogenesis and clinicopathologic characteristics of recurrent carotid disease. J Vasc Surg. 1986 Jan;3(1):10-23.  PMID: 3941478
  146. Atkinson JB, Forman MB, Vaughn WK, Robinowitz M, McAllister HA, Virmani R. Morphologic changes in long-term saphenous vein bypass grafts. Chest. 1985 Sep;88(3):341-8. PMID: 3875453
  147. Atkinson JB, Robinowitz M, McAllister HA, Virmani R.  Association of eosinophils with cardiac rupture. Hum Pathol. 1985 Jun;16(6):562-8. PMID: 3997134
  148. Atkinson JB, Forman MB, Perry JM, Virmani R.  Correlation of saphenous vein bypass graft angiograms with histologic changes at necropsy. Am J Cardiol. 1985 Apr 1;55(8):952-5. PMID: 3872590
  149. Virmani R, Robinowitz M, McAllister HA Jr.  Coronary heart disease in 48 autopsy patients 30 years old and younger. Arch Pathol Lab Med. 1983 Oct;107(10):535-40. PMID: 6688516
  150. Virmani R, Robinowitz M, McAllister HA Jr.  Nontraumatic death in joggers. A series of 30 patients at autopsy. Am J Med. 1982 Jun;72(6):874-82. PMID: 6211977
  151. Michel JB, Virmani R, Arbustini E, Pasterkamp G. Intraplaque haemorrhages as the trigger of plaque vulnerability. Eur Heart J. Aug 2011;32(16):1977-1985, 1985a, 1985b, 1985c.
  152. Alfonso F, Virmani R. New morphological insights on coronary plaque rupture: bridging the gap from anatomy to clinial presentation? JACC Cardiovasc Interv. Jan 2011;4(1):83-86.
  153. Yazdani SK, Vorpahl M, Ladich E, Virmani R. Pathology and vulnerability of atherosclerotic plaque: identification, treatment options, and individual patient differences for prevention of stroke. Curr Treat Options Cardiovasc Med. Jun 2010;12(3):297-314.
  154. Yazdani SK, Nakano M, Otsuka F, Kolodgie FD, Virmani R. Atheroma and coronary bifurcations: before and after stenting. EuroIntervention. Dec 2010;6 Suppl J:J24-30.
  155. van Dijk RA, Virmani R, von der Thusen JH, Schaapherder AF, Lindeman JH. The natural history of aortic atherosclerosis: a systematic histopathological evaluation of the peri-renal region. Atherosclerosis. May 2010;210(1):100-106.
  156. Mauriello A, Sangiorgi GM, Virmani R, Trimarchi S, Holmes DR, Jr., Kolodgie FD, Piepgras DG, Piperno G, Liotti D, Narula J, Righini P, Ippoliti A, Spagnoli LG. A pathobiologic link between risk factors profile and morphological markers of carotid instability. Atherosclerosis. Feb 2010;208(2):572-580.
  157. Kramer MC, Rittersma SZ, de Winter RJ, Ladich ER, Fowler DR, Liang YH, Kutys R, Carter-Monroe N, Kolodgie FD, van der Wal AC, Virmani R. Relationship of thrombus healing to underlying plaque morphology in sudden coronary death. J Am Coll Cardiol. Jan 12 2010;55(2):122-132.
  158. Finn AV, Kolodgie FD, Virmani R. Correlation between carotid intimal/medial thickness and atherosclerosis: a point of view from pathology. Arterioscler Thromb Vasc Biol. Feb 2010;30(2):177-181.
  159. Finn AV, Kolodgie FD, Nakano M, Virmani R. The differences between neovascularization of chronic total occlusion and intraplaque angiogenesis. JACC Cardiovasc Imaging. Aug 2010;3(8):806-810.
  160. Ferrante G, Nakano M, Prati F, Niccoli G, Mallus MT, Ramazzotti V, Montone RA, Kolodgie FD, Virmani R, Crea F. High levels of systemic myeloperoxidase are associated with coronary plaque erosion in patients with acute coronary syndromes: a clinicopathological study. Circulation. Dec 14 2010;122(24):2505-2513. PMID: 21126969
  161. Virmani R, Finn AV, Kolodgie FD. Carotid plaque stabilization and progression after stroke or TIA. Arterioscler Thromb Vasc Biol. Jan 2009;29(1):3-6.
  162. Sluimer JC, Kolodgie FD, Bijnens AP, Maxfield K, Pacheco E, Kutys B, Duimel H, Frederik PM, van Hinsbergh VW, Virmani R, Daemen MJ. Thin-walled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions relevance of compromised structural integrity for intraplaque microvascular leakage. J Am Coll Cardiol. Apr 28 2009;53(17):1517-1527.
  163. Schwartz RS, Burke A, Farb A, Kaye D, Lesser JR, Henry TD, Virmani R. Microemboli and microvascular obstruction in acute coronary thrombosis and sudden coronary death: relation to epicardial plaque histopathology. J Am Coll Cardiol. Dec 1 2009;54(23):2167-2173.
  164. Fu Z, Wang M, Gucek M, Zhang J, Wu J, Jiang L, Monticone RE, Khazan B, Telljohann R, Mattison J, Sheng S, Cole RN, Spinetti G, Pintus G, Liu L, Kolodgie FD, Virmani R, Spurgeon H, Ingram DK, Everett AD, Lakatta EG, Van Eyk JE. Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion. Circ Res. Jun 19 2009;104(12):1337-1346.
  165. Lim WS, Timmins JM, Seimon TA, Sadler A, Kolodgie FD, Virmani R, Tabas I. Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. Circulation. Feb 19 2008;117(7):940-951.
  166. Wang M, Zhang J, Jiang LQ, Spinetti G, Pintus G, Monticone R, Kolodgie FD, Virmani R, Lakatta EG. Proinflammatory profile within the grossly normal aged human aortic wall. Hypertension. Jul 2007;50(1):219-227.
  167. Kolodgie FD, Narula J, Yuan C, Burke AP, Finn AV, Virmani R. Elimination of neoangiogenesis for plaque stabilization: is there a role for local drug therapy? J Am Coll Cardiol. May 29 2007;49(21):2093-2101.
  168. Kolodgie FD, Burke AP, Nakazawa G, Virmani R. Is pathologic intimal thickening the key to understanding early plaque progression in human atherosclerotic disease? Arterioscler Thromb Vasc Biol. May 2007;27(5):986-989.
  169. Kolodgie FD, Burke AP, Nakazawa G, Cheng Q, Xu X, Virmani R. Free cholesterol in atherosclerotic plaques: where does it come from? Curr Opin Lipidol. Oct 2007;18(5):500-507.
  170. Jain RK, Finn AV, Kolodgie FD, Gold HK, Virmani R. Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization. Nat Clin Pract Cardiovasc Med. Sep 2007;4(9):491-502.
  171. Virmani R, Ladich ER, Burke AP, Kolodgie FD. Histopathology of carotid atherosclerotic disease. Neurosurgery. Nov 2006;59(5 Suppl 3):S219-227; discussion S213-213.
  172. Virmani R, Burke AP, Kolodgie F. Morphological characteristics of coronary atherosclerosis in diabetes mellitus. Can J Cardiol. Feb 2006;22 Suppl B:81B-84B.
  173. Virmani R, Burke AP, Farb A, Kolodgie FD. Pathology of the vulnerable plaque. J Am Coll Cardiol. Apr 18 2006;47(8 Suppl):C13-18.
  174. Verhoeven BA, Moll FL, Koekkoek JA, van der Wal AC, de Kleijn DP, de Vries JP, Verheijen JH, Velema E, Busser E, Schoneveld A, Virmani R, Pasterkamp G. Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy. Stroke. Aug 2006;37(8):2054-2060.
  175. Kolodgie FD, Burke AP, Skorija KS, Ladich E, Kutys R, Makuria AT, Virmani R. Lipoprotein-associated phospolipase A2 protein expression in the natural progression of human coronary atherosclerosis. Arterioscler Thromb Vasc Biol. Nov 2006;26(11):2523-2529.
  176. Hao H, Gabbiani G, Camenzind E, Bacchetta M, Virmani R, Bochaton-Piallat ML. Phenotypic modulation of intima and media smooth muscle cells in fatal cases of coronary artery lesion. Arterioscler Thromb Vasc Biol. Feb 2006;26(2):326-332.
  177. Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, Wrenn SP, Narula J. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol. Oct 2005;25(10):2054-2061.
  178. Hartung D, Sarai M, Petrov A, Kolodgie F, Narula N, Verjans J, Virmani R, Reutelingsperger C, Hofstra L, Narula J. Resolution of apoptosis in atherosclerotic plaque by dietary modification and statin therapy. J Nucl Med. Dec 2005;46(12):2051-2056.
  179. Schaar JA, Muller JE, Falk E, Virmani R, Fuster V, Serruys PW, Colombo A, Stefanadis C, Ward Casscells S, Moreno PR, Maseri A, van der Steen AF. Terminology for high-risk and vulnerable coronary artery plaques. Report of a meeting on the vulnerable plaque, June 17 and 18, 2003, Santorini, Greece. Eur Heart J. Jun 2004;25(12):1077-1082.
  180. Kolodgie FD, Virmani R, Burke AP, Farb A, Weber DK, Kutys R, Finn AV, Gold HK. Pathologic assessment of the vulnerable human coronary plaque. Heart. Dec 2004;90(12):1385-1391.
  181. Kolodgie FD, Burke AP, Wight TN, Virmani R. The accumulation of specific types of proteoglycans in eroded plaques: a role in coronary thrombosis in the absence of rupture. Curr Opin Lipidol. Oct 2004;15(5):575-582.
  182. Fischer JW, Steitz SA, Johnson PY, Burke A, Kolodgie F, Virmani R, Giachelli C, Wight TN. Decorin promotes aortic smooth muscle cell calcification and colocalizes to calcified regions in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol. Dec 2004;24(12):2391-2396.
  183. Farb A, Kolodgie FD, Hwang JY, Burke AP, Tefera K, Weber DK, Wight TN, Virmani R. Extracellular matrix changes in stented human coronary arteries. Circulation. Aug 24 2004;110(8):940-947.
  184. Burke AP, Kolodgie FD, Zieske A, Fowler DR, Weber DK, Varghese PJ, Farb A, Virmani R. Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study. Arterioscler Thromb Vasc Biol. Jul 2004;24(7):1266-1271.
  185. Virmani R, Burke AP, Kolodgie FD, Farb A. Pathology of the thin-cap fibroatheroma: a type of vulnerable plaque. J Interv Cardiol. Jun 2003;16(3):267-272.
  186. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Jr., Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation. Oct 14 2003;108(15):1772-1778.
  187. Kolodgie FD, Gold HK, Burke AP, Fowler DR, Kruth HS, Weber DK, Farb A, Guerrero LJ, Hayase M, Kutys R, Narula J, Finn AV, Virmani R. Intraplaque hemorrhage and progression of coronary atheroma. N Engl J Med. Dec 11 2003;349(24):2316-2325.
  188. Farb A, Burke AP, Kolodgie FD, Virmani R. Pathological mechanisms of fatal late coronary stent thrombosis in humans. Circulation. Oct 7 2003;108(14):1701-1706.
  189. Burke AP, Virmani R, Galis Z, Haudenschild CC, Muller JE. 34th Bethesda Conference: Task force #2–What is the pathologic basis for new atherosclerosis imaging techniques? J Am Coll Cardiol. Jun 4 2003;41(11):1874-1886.
  190. Virmani R, Burke AP, Farb A, Kolodgie FD. Pathology of the unstable plaque. Prog Cardiovasc Dis. Mar-Apr 2002;44(5):349-356.
  191. Kolodgie FD, Burke AP, Farb A, Weber DK, Kutys R, Wight TN, Virmani R. Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion. Arterioscler Thromb Vasc Biol. Oct 1 2002;22(10):1642-1648.
  192. Burke AP, Tracy RP, Kolodgie F, Malcom GT, Zieske A, Kutys R, Pestaner J, Smialek J, Virmani R. Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies. Circulation. Apr 30 2002;105(17):2019-2023.
  193. Burke AP, Kolodgie FD, Farb A, Weber D, Virmani R. Morphological predictors of arterial remodeling in coronary atherosclerosis. Circulation. Jan 22 2002;105(3):297-303.
  194. Burke AP, Fonseca V, Kolodgie F, Zieske A, Fink L, Virmani R. Increased serum homocysteine and sudden death resulting from coronary atherosclerosis with fibrous plaques. Arterioscler Thromb Vasc Biol. Nov 1 2002;22(11):1936-1941.
  195. Burke AP, Farb A, Pestaner J, Malcom GT, Zieske A, Kutys R, Smialek J, Virmani R. Traditional risk factors and the incidence of sudden coronary death with and without coronary thrombosis in blacks. Circulation. Jan 29 2002;105(4):419-424.
  196. Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P. Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am J Pathol. Mar 2001;158(3):879-891.
  197. Schmermund A, Schwartz RS, Adamzik M, Sangiorgi G, Pfeifer EA, Rumberger JA, Burke AP, Farb A, Virmani R. Coronary atherosclerosis in unheralded sudden coronary death under age 50: histo-pathologic comparison with ‘healthy’ subjects dying out of hospital. Atherosclerosis. Apr 2001;155(2):499-508.
  198. Kolodgie FD, Narula J, Haider N, Virmani R. Apoptosis in atherosclerosis. Does it contribute to plaque instability? Cardiol Clin. Feb 2001;19(1):127-139, ix.
  199. Kolodgie FD, Burke AP, Farb A, Gold HK, Yuan J, Narula J, Finn AV, Virmani R. The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes. Curr Opin Cardiol. Sep 2001;16(5):285-292.
  200. Burke AP, Weber DK, Kolodgie FD, Farb A, Taylor AJ, Virmani R. Pathophysiology of calcium deposition in coronary arteries. Herz. Jun 2001;26(4):239-244.
  201. Burke AP, Kolodgie FD, Farb A, Weber DK, Malcom GT, Smialek J, Virmani R. Healed plaque ruptures and sudden coronary death: evidence that subclinical rupture has a role in plaque progression. Circulation. Feb 20 2001;103(7):934-940.
  202. Burke AP, Farb A, Malcom G, Virmani R. Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis. Am Heart J. Feb 2001;141(2 Suppl):S58-62.
  203. Bayes-Genis A, Conover CA, Overgaard MT, Bailey KR, Christiansen M, Holmes DR, Jr., Virmani R, Oxvig C, Schwartz RS. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med. Oct 4 2001;345(14):1022-1029.
  204. Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol. May 2000;20(5):1262-1275.
  205. Taylor AJ, Burke AP, O’Malley PG, Farb A, Malcom GT, Smialek J, Virmani R. A comparison of the Framingham risk index, coronary artery calcification, and culprit plaque morphology in sudden cardiac death. Circulation. Mar 21 2000;101(11):1243-1248.
  206. Schwartz SM, Virmani R, Rosenfeld ME. The good smooth muscle cells in atherosclerosis. Curr Atheroscler Rep. Sep 2000;2(5):422-429.
  207. Schneider DB, Vassalli G, Wen S, Driscoll RM, Sassani AB, DeYoung MB, Linnemann R, Virmani R, Dichek DA. Expression of Fas ligand in arteries of hypercholesterolemic rabbits accelerates atherosclerotic lesion formation. Arterioscler Thromb Vasc Biol. Feb 2000;20(2):298-308.
  208. Rosenfeld ME, Polinsky P, Virmani R, Kauser K, Rubanyi G, Schwartz SM. Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse. Arterioscler Thromb Vasc Biol. Dec 2000;20(12):2587-2592.
  209. Mauriello A, Sangiorgi G, Palmieri G, Virmani R, Holmes DR, Jr., Schwartz RS, Pistolese R, Ippoliti A, Spagnoli LG. Hyperfibrinogenemia is associated with specific histocytological composition and complications of atherosclerotic carotid plaques in patients affected by transient ischemic attacks. Circulation. Feb 22 2000;101(7):744-750.
  210. Kolodgie FD, Narula J, Burke AP, Haider N, Farb A, Hui-Liang Y, Smialek J, Virmani R. Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death. Am J Pathol. Oct 2000;157(4):1259-1268.
  211. Burke AP, Taylor A, Farb A, Malcom GT, Virmani R. Coronary calcification: insights from sudden coronary death victims. Z Kardiol. 2000;89 Suppl 2:49-53.
  212. Burke A, Virmani R. Significance of multiple coronary artery thrombi. A consequence of diffuse atherosclerotic disease? Ital Heart J. Dec 2000;1(12):832-834.
  213. Virmani R, Popovsky MA, Roberts WC.  Thrombocytosis, coronary thrombosis and acute myocardial infarction. Am J Med. 1979 Sep;67(3):498-506. PMID: 474596