Publications

Biomechanics of Atherosclerosis

  1. Campbell IC1, Weiss D, Suever JD, Virmani R, Veneziani A, Vito RP, Oshinski JN, Taylor WR. Biomechanical modeling and morphology analysis indicates plaque rupture due to mechanical failure unlikely in atherosclerosis-prone mice.Am J Physiol Heart Circ Physiol. 2013 Feb 1;304(3):H473-86. doi: 10.1152/ajpheart.00620.2012. Epub 2012 Nov 30
  2. Campbell IC, Timmins LH, Giddens DP, Virmani R, Veneziani A, Rab ST, Samady H, McDaniel MC, Finn AV, Taylor WR, Oshinski JN. Computational Fluid Dynamics Simulations of Hemodynamics in Plaque Erosion.  Cardiovasc Eng Technol.  2013. PubMed PMID:24223678
  3. Campbell IC, Suever JD, Timmins LH, Veneziani A, Vito RP, Virmani R, Oshinski JN, Taylor WR. Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women.  PLoS One.  2014.  PubMed PMID:25365517
  4. Kwak BR, Bck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJ, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ, Evans PC. Biomechanical factors in atherosclerosis: mechanisms and clinical implications. Eur Heart J.  2014. PubMed PMID:25230814
  5. Speelman L, Akyildiz AC, den Adel B, Wentzel JJ, van der Steen AF, Virmani R, van der Weerd L, Jukema JW, Poelmann RE, van Brummelen EH, Gijsen FJ. Initial stress in biomechanical models of atherosclerotic plaques. J Biomech. Sep 2 2011;44(13):2376-2382.
  6. Akyildiz AC, Speelman L, van Brummelen H, Gutierrez MA, Virmani R, van der Lugt A, van der Steen AF, Wentzl JJ, Gijsen FJ. Effects of intima stiffness and plaque morphology on peak cap stress. Biomed Eng Online. 2011;1:25.
  7. Vengrenyuk Y, Carlier S, Xanthos S, Cardoso L, Ganatos P, Virmani R, Einav S, Gilchrist L, Weinbaum S. A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps. Proc Natl Acad Sci U S A. Oct 3 2006;103(40):14678-14683.
  8. Huang H, Virmani R, Younis H, Burke AP, Kamm RD, Lee RT. The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation. Feb 27 2001;103(8):1051-1056.